Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling

Understanding the regulatory mechanisms unique to breast cancer stem cells (BCSCs) is required to control breast cancer metastasis. We found that phthalates promote BCSCs in human breast cancer cell cultures and xenograft tumors. A toxic phthalate, benzyl butyl phthalate (BBP), activated aryl hydroc...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Chih, Tsai, Cheng-Fang, Chuang, Hsiao-Li, Chang, Yi-Chih, Chen, Hung-Sheng, Lee, Jau-Nan, Tsai, Eing-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045417/
https://www.ncbi.nlm.nih.gov/pubmed/27129165
http://dx.doi.org/10.18632/oncotarget.9007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045417/
https://www.ncbi.nlm.nih.gov/pubmed/27129165
http://dx.doi.org/10.18632/oncotarget.9007

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