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Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling
Understanding the regulatory mechanisms unique to breast cancer stem cells (BCSCs) is required to control breast cancer metastasis. We found that phthalates promote BCSCs in human breast cancer cell cultures and xenograft tumors. A toxic phthalate, benzyl butyl phthalate (BBP), activated aryl hydroc...
Autores principales: | Wang, Yu-Chih, Tsai, Cheng-Fang, Chuang, Hsiao-Li, Chang, Yi-Chih, Chen, Hung-Sheng, Lee, Jau-Nan, Tsai, Eing-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045417/ https://www.ncbi.nlm.nih.gov/pubmed/27129165 http://dx.doi.org/10.18632/oncotarget.9007 |
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