The La protein counteracts cisplatin-induced cell death by stimulating protein synthesis of anti-apoptotic factor Bcl2

Up-regulation of anti-apoptotic factors is a critical mechanism of cancer cell resistance and often counteracts the success of chemotherapeutic treatment. Herein, we identified the cancer-associated RNA-binding protein La as novel factor contributing to cisplatin resistance. Our data demonstrate tha...

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Detalles Bibliográficos
Autores principales: Heise, Tilman, Kota, Venkatesh, Brock, Alexander, Morris, Amanda B., Rodriguez, Reycel M., Zierk, Avery W., Howe, Philip H., Sommer, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045424/
https://www.ncbi.nlm.nih.gov/pubmed/27105491
http://dx.doi.org/10.18632/oncotarget.8819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045424/
https://www.ncbi.nlm.nih.gov/pubmed/27105491
http://dx.doi.org/10.18632/oncotarget.8819

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