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The La protein counteracts cisplatin-induced cell death by stimulating protein synthesis of anti-apoptotic factor Bcl2

Up-regulation of anti-apoptotic factors is a critical mechanism of cancer cell resistance and often counteracts the success of chemotherapeutic treatment. Herein, we identified the cancer-associated RNA-binding protein La as novel factor contributing to cisplatin resistance. Our data demonstrate tha...

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Detalles Bibliográficos
Autores principales:	Heise, Tilman, Kota, Venkatesh, Brock, Alexander, Morris, Amanda B., Rodriguez, Reycel M., Zierk, Avery W., Howe, Philip H., Sommer, Gunhild
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045424/ https://www.ncbi.nlm.nih.gov/pubmed/27105491 http://dx.doi.org/10.18632/oncotarget.8819

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