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The transcription factor RUNX2 regulates receptor tyrosine kinase expression in melanoma

Receptor tyrosine kinases-based autocrine loops largely contribute to activate the MAPK and PI3K/AKT pathways in melanoma. However, the molecular mechanisms involved in generating these autocrine loops are still largely unknown. In the present study, we examine the role of the transcription factor R...

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Detalles Bibliográficos
Autores principales: Boregowda, Rajeev K., Medina, Daniel J., Markert, Elke, Bryan, Michael A., Chen, Wenjin, Chen, Suzie, Rabkin, Anna, Vido, Michael J., Gunderson, Samuel I., Chekmareva, Marina, Foran, David J., Lasfar, Ahmed, Goydos, James S., Cohen-Solal, Karine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045426/
https://www.ncbi.nlm.nih.gov/pubmed/27102439
http://dx.doi.org/10.18632/oncotarget.8822