Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol

Elevated basal insulin secretion under fasting conditions together with insufficient stimulated insulin release is an important hallmark of type 2 diabetes, but the mechanisms controlling basal insulin secretion remain unclear. Membrane rafts exist in pancreatic islet cells and spatially organize me...

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Detalles Bibliográficos
Autores principales: Nagaraj, Vini, Kazim, Abdulla S., Helgeson, Johan, Lewold, Clemens, Barik, Satadal, Buda, Pawel, Reinbothe, Thomas M., Wennmalm, Stefan, Zhang, Enming, Renström, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045496/
https://www.ncbi.nlm.nih.gov/pubmed/27533789
http://dx.doi.org/10.1210/me.2016-1023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045496/
https://www.ncbi.nlm.nih.gov/pubmed/27533789
http://dx.doi.org/10.1210/me.2016-1023

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