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Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol
Elevated basal insulin secretion under fasting conditions together with insufficient stimulated insulin release is an important hallmark of type 2 diabetes, but the mechanisms controlling basal insulin secretion remain unclear. Membrane rafts exist in pancreatic islet cells and spatially organize me...
Autores principales: | Nagaraj, Vini, Kazim, Abdulla S., Helgeson, Johan, Lewold, Clemens, Barik, Satadal, Buda, Pawel, Reinbothe, Thomas M., Wennmalm, Stefan, Zhang, Enming, Renström, Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045496/ https://www.ncbi.nlm.nih.gov/pubmed/27533789 http://dx.doi.org/10.1210/me.2016-1023 |
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