A brief history of the discovery of PXR and CAR as xenobiotic receptors

The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) were cloned and/or established as xenobiotic receptors in 1998. Due to their activities in the transcriptional regulation of phase I and phase II enzymes as well as drug transporters, PXR and CAR have been def...

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Detalles Bibliográficos
Autores principales: Yan, Jiong, Xie, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045536/
https://www.ncbi.nlm.nih.gov/pubmed/27709013
http://dx.doi.org/10.1016/j.apsb.2016.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045536/
https://www.ncbi.nlm.nih.gov/pubmed/27709013
http://dx.doi.org/10.1016/j.apsb.2016.06.011

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