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Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids
The liver is essential for survival due to its critical role in the regulation of metabolic homeostasis. Metabolism of xenobiotics, such as environmental chemicals and drugs by the liver protects us from toxic effects of these xenobiotics, whereas metabolism of cholesterol, bile acids (BAs), lipids,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045537/ https://www.ncbi.nlm.nih.gov/pubmed/27709008 http://dx.doi.org/10.1016/j.apsb.2016.07.003 |