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An update on the role of intestinal cytochrome P450 enzymes in drug disposition
Oral administration is the most commonly used route for drug treatment. Intestinal cytochrome P450 (CYP)-mediated metabolism can eliminate a large proportion of some orally administered drugs before they reach systemic circulation, while leaving the passage of other drugs unimpeded. A better underst...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045550/ https://www.ncbi.nlm.nih.gov/pubmed/27709006 http://dx.doi.org/10.1016/j.apsb.2016.07.012 |