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An update on the role of intestinal cytochrome P450 enzymes in drug disposition

Oral administration is the most commonly used route for drug treatment. Intestinal cytochrome P450 (CYP)-mediated metabolism can eliminate a large proportion of some orally administered drugs before they reach systemic circulation, while leaving the passage of other drugs unimpeded. A better underst...

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Detalles Bibliográficos
Autores principales: Xie, Fang, Ding, Xinxin, Zhang, Qing-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045550/
https://www.ncbi.nlm.nih.gov/pubmed/27709006
http://dx.doi.org/10.1016/j.apsb.2016.07.012