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High nuclear expression of proteasome activator complex subunit 1 predicts poor survival in soft tissue leiomyosarcomas

BACKGROUND: Previous studies on high grade sarcomas using mass spectrometry imaging showed proteasome activator complex subunit 1 (PSME1) to be associated with poor survival in soft tissue sarcoma patients. PSME1 is involved in immunoproteasome assembly for generating tumor antigens presented by MHC...

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Detalles Bibliográficos
Autores principales: Lou, Sha, Cleven, Arjen H. G., Balluff, Benjamin, de Graaff, Marieke, Kostine, Marie, Briaire-de Bruijn, Inge, McDonnell, Liam A., Bovée, Judith V. M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045577/
https://www.ncbi.nlm.nih.gov/pubmed/27733900
http://dx.doi.org/10.1186/s13569-016-0057-z