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PERK regulates G(q) protein-coupled intracellular Ca(2+) dynamics in primary cortical neurons
PERK (EIF2AK3) is an ER-resident eIF2α kinase required for behavioral flexibility and metabotropic glutamate receptor-dependent long-term depression via its translational control. Motivated by the recent discoveries that PERK regulates Ca(2+) dynamics in insulin-secreting β-cells underlying glucose-...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045583/ https://www.ncbi.nlm.nih.gov/pubmed/27716400 http://dx.doi.org/10.1186/s13041-016-0268-5 |