Cargando…
PERK regulates G(q) protein-coupled intracellular Ca(2+) dynamics in primary cortical neurons
PERK (EIF2AK3) is an ER-resident eIF2α kinase required for behavioral flexibility and metabotropic glutamate receptor-dependent long-term depression via its translational control. Motivated by the recent discoveries that PERK regulates Ca(2+) dynamics in insulin-secreting β-cells underlying glucose-...
Autores principales: | Zhu, Siying, McGrath, Barbara C., Bai, Yuting, Tang, Xin, Cavener, Douglas R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045583/ https://www.ncbi.nlm.nih.gov/pubmed/27716400 http://dx.doi.org/10.1186/s13041-016-0268-5 |
Ejemplares similares
-
PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility
por: Zhu, Siying, et al.
Publicado: (2016) -
Perk Gene Dosage Regulates Glucose Homeostasis by Modulating Pancreatic β-Cell Functions
por: Wang, Rong, et al.
Publicado: (2014) -
PERK Regulates the Proliferation and Development of Insulin-Secreting Beta-Cell Tumors in the Endocrine Pancreas of Mice
por: Gupta, Sounak, et al.
Publicado: (2009) -
PERK (EIF2AK3) Regulates Proinsulin Trafficking and Quality Control in the Secretory Pathway
por: Gupta, Sounak, et al.
Publicado: (2010) -
Correction: PERK Regulates the Proliferation and Development of Insulin-Secreting Beta-Cell Tumors in the Endocrine Pancreas of Mice
por: Gupta, Sounak, et al.
Publicado: (2009)