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Exosomes derived from HCC cells induce sorafenib resistance in hepatocellular carcinoma both in vivo and in vitro

BACKGROUND: Exosomes are carriers of intercellular information and regulate the tumor microenvironment. They play an important role in drug resistance by transporting RNA molecules and proteins. However, their effects on sorafenib resistance in hepatocellular carcinoma (HCC) are not completely under...

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Detalles Bibliográficos
Autores principales: Qu, Zhen, Wu, Junhua, Wu, Junyi, Luo, Dongjun, Jiang, Chunping, Ding, Yitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045585/
https://www.ncbi.nlm.nih.gov/pubmed/27716356
http://dx.doi.org/10.1186/s13046-016-0430-z