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Identification of replication-dependent and replication-independent linker histone complexes: Tpr specifically promotes replication-dependent linker histone stability

BACKGROUND: There are 11 variants of linker histone H1 in mammalian cells. Beyond their shared abilities to stabilize and condense chromatin, the H1 variants have been found to have non-redundant functions, the mechanisms of which are not fully understood. Like core histones, there are both replicat...

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Detalles Bibliográficos
Autores principales: Zhang, Pei, Branson, Owen E., Freitas, Michael A., Parthun, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045598/
https://www.ncbi.nlm.nih.gov/pubmed/27716023
http://dx.doi.org/10.1186/s12858-016-0074-9