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DNA replication stress: a source of APOBEC3B expression in breast cancer
APOBEC cytidine deaminases have been implicated as major contributors to the mutation burden in many cancers on the basis of their mutational signature. A new experimental study sheds light on the inciting factors, linking APOBEC3B expression to oncogene- and drug-induced replication stress. ELECTRO...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045630/ https://www.ncbi.nlm.nih.gov/pubmed/27716362 http://dx.doi.org/10.1186/s13059-016-1069-y |