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DNA replication stress: a source of APOBEC3B expression in breast cancer

APOBEC cytidine deaminases have been implicated as major contributors to the mutation burden in many cancers on the basis of their mutational signature. A new experimental study sheds light on the inciting factors, linking APOBEC3B expression to oncogene- and drug-induced replication stress. ELECTRO...

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Detalles Bibliográficos
Autores principales: Cescon, David W., Haibe-Kains, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045630/
https://www.ncbi.nlm.nih.gov/pubmed/27716362
http://dx.doi.org/10.1186/s13059-016-1069-y