Effects of Lemon and Seville Orange Juices on the Pharmacokinetic Properties of Sildenafil in Healthy Subjects

PURPOSE: Several severe drug interactions have been reported when sildenafil, a potent drug for the treatment of erectile dysfunction, is co-administered with drugs or herbal remedies that inhibit cytochrome P450 (CYP) 3A4. This study evaluates the effects of two citrus fruit juices, lemon and Sevil...

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Detalles Bibliográficos
Autores principales: Abdelkawy, Khaled S., Donia, Ahmed M., Turner, R. Brigg, Elbarbry, Fawzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045831/
https://www.ncbi.nlm.nih.gov/pubmed/27550653
http://dx.doi.org/10.1007/s40268-016-0140-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045831/
https://www.ncbi.nlm.nih.gov/pubmed/27550653
http://dx.doi.org/10.1007/s40268-016-0140-1

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