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Structural insights into the polypharmacological activity of quercetin on serine/threonine kinases

Polypharmacology, the discovery or design of drug molecules that can simultaneously interact with multiple targets, is gaining interest in contemporary drug discovery. Serine/threonine kinases are attractive targets for therapeutic intervention in oncology due to their role in cellular phosphorylati...

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Detalles Bibliográficos
Autores principales: Baby, Bincy, Antony, Priya, Al Halabi, Walaa, Al Homedi, Zahrah, Vijayan, Ranjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045902/
https://www.ncbi.nlm.nih.gov/pubmed/27729770
http://dx.doi.org/10.2147/DDDT.S118423