Population pharmacokinetic and pharmacodynamic analyses of safinamide in subjects with Parkinson's disease

Safinamide is an orally administered α‐aminoamide derivative with both dopaminergic and non‐dopaminergic properties. Nonlinear mixed effects models for population pharmacokinetic (PK) and pharmacokinetic–pharmacodynamic (PKPD) analyses were developed using records from, respectively, 623 and 668 pat...

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Detalles Bibliográficos
Autores principales: Loprete, Luca, Leuratti, Chiara, Cattaneo, Carlo, Thapar, Mita M., Farrell, Colm, Sardina, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045937/
https://www.ncbi.nlm.nih.gov/pubmed/27713822
http://dx.doi.org/10.1002/prp2.251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045937/
https://www.ncbi.nlm.nih.gov/pubmed/27713822
http://dx.doi.org/10.1002/prp2.251

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