Phenotyping and genotyping of CYP2C19 using comparative metabolism of proguanil in sickle‐cell disease patients and healthy controls in Nigeria

Polymorphic expression of metabolic enzymes have been identified as one of the key factors responsible for the interindividual/ethnic/racial variability in drug metabolism and effect. In Nigeria, there is a disproportionately high incidence of sickle‐cell disease (SCD), a condition characterized by...

Descripción completa

Detalles Bibliográficos
Autores principales: Adejumo, Olufunmilayo E., Kotila, Taiwo R., Falusi, Adeyinka G., Silva, Boladale O., Nwogu, Jacinta N., Fasinu, Pius S., Babalola, Chinedum P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045938/
https://www.ncbi.nlm.nih.gov/pubmed/27713823
http://dx.doi.org/10.1002/prp2.252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045938/
https://www.ncbi.nlm.nih.gov/pubmed/27713823
http://dx.doi.org/10.1002/prp2.252

Ejemplares similares