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Protein arginylation regulates cellular stress response by stabilizing HSP70 and HSP40 transcripts

ATE1-mediated post-translational addition of arginine to a protein has been shown to regulate activity, interaction, and stability of the protein substrates. Arginylation has been linked to many different stress conditions, namely ER stress, cytosolic misfolded protein stress, and nitrosative stress...

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Detalles Bibliográficos
Autores principales: Deka, Kamalakshi, Singh, Archana, Chakraborty, Surajit, Mukhopadhyay, Rupak, Saha, Sougata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045964/
https://www.ncbi.nlm.nih.gov/pubmed/27752365
http://dx.doi.org/10.1038/cddiscovery.2016.74