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Reduced lipolysis response to adipose afferent reflex involved in impaired activation of adrenoceptor-cAMP-PKA-hormone sensitive lipase pathway in obesity

Chemical stimulation of white adipose tissue (WAT) causes adipose afferent reflex (AAR) and sympathetic activation. This study is to investigate the effects of AAR on lipolysis and the mechanisms of attenuated lipolysis response to enhanced AAR in obesity. Obesity was caused by high-fat diet for 12...

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Detalles Bibliográficos
Autores principales: Ding, Lei, Zhang, Feng, Zhao, Ming-Xia, Ren, Xing-Sheng, Chen, Qi, Li, Yue-Hua, Kang, Yu-Ming, Zhu, Guo-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046068/
https://www.ncbi.nlm.nih.gov/pubmed/27694818
http://dx.doi.org/10.1038/srep34374