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Prediction and evaluation of the lipase inhibitory activities of tea polyphenols with 3D-QSAR models

The extraordinary hypolipidemic effects of polyphenolic compounds from tea have been confirmed in our previous study. To gain compounds with more potent activities, using the conformations of the most active compound revealed by molecular docking, a 3D-QSAR pancreatic lipase inhibitor model with goo...

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Detalles Bibliográficos
Autores principales: Li, Yi-Fang, Chang, Yi-Qun, Deng, Jie, Li, Wei-Xi, Jian, Jie, Gao, Jia-Suo, Wan, Xin, Gao, Hao, Kurihara, Hiroshi, Sun, Ping-Hua, He, Rong-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046073/
https://www.ncbi.nlm.nih.gov/pubmed/27694956
http://dx.doi.org/10.1038/srep34387