Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway

Indatraline is an antidepressive agent and a non-selective monoamine transporter inhibitor that blocks the reuptake of neurotransmitters (dopamine, serotonin, and norepinephrine). In this study, we report that indatraline induces autophagy via the suppression of mTOR/S6 kinase signaling. Autophagy i...

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Detalles Bibliográficos
Autores principales: Cho, Yoon Sun, Yen, Chih-na, Shim, Joong Sup, Kang, Dong Hoon, Kang, Sang Won, Liu, Jun O., Kwon, Ho Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046148/
https://www.ncbi.nlm.nih.gov/pubmed/27694974
http://dx.doi.org/10.1038/srep34655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046148/
https://www.ncbi.nlm.nih.gov/pubmed/27694974
http://dx.doi.org/10.1038/srep34655

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