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γ-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules

BACKGROUND: Colorectal cancer (CRC) is one of the most common malignancies worldwide and even develops resistance to chemotherapeutic agents over time. As a result survival for patients with CRC remains poor. METHOD: We investigated both in vitro and in vivo effects of γ-tocotrienol (γ-T3) alone and...

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Detalles Bibliográficos
Autores principales: Prasad, Sahdeo, Gupta, Subash C, Tyagi, Amit K, Aggarwal, Bharat B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046209/
https://www.ncbi.nlm.nih.gov/pubmed/27575851
http://dx.doi.org/10.1038/bjc.2016.257