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Development of an Acid-Resistant Salmonella Typhi Ty21a Attenuated Vector For Improved Oral Vaccine Delivery

The licensed oral, live-attenuated bacterial vaccine for typhoid fever, Salmonella enterica serovar Typhi strain Ty21a, has also been utilized as a vaccine delivery platform for expression of diverse foreign antigens that stimulate protection against shigellosis, anthrax, plague, or human papilloma...

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Detalles Bibliográficos
Autores principales: Dharmasena, Madushini N., Feuille, Catherine M., Starke, Carly Elizabeth C., Bhagwat, Arvind A., Stibitz, Scott, Kopecko, Dennis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046385/
https://www.ncbi.nlm.nih.gov/pubmed/27673328
http://dx.doi.org/10.1371/journal.pone.0163511