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Epitope Capsid-Incorporation: A New Effective Approach for Vaccine Development for Chagas Disease

BACKGROUND: Previously we reported that a hexon-modified adenovirus (Ad) vector containing the invasive neutralizing epitope of Trypanosoma cruzi (T. cruzi) trypomastigote gp83 (Ad5-gp83) provided immunoprotection against T. cruzi infection. The purpose of this work was to design an improved vaccine...

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Detalles Bibliográficos
Autores principales: Matthews, Qiana L., Farrow, Anitra L., Rachakonda, Girish, Gu, Linlin, Nde, Pius, Krendelchtchikov, Alexandre, Pratap, Siddharth, Sakhare, Shruti S., Sabbaj, Steffanie, Lima, Maria F., Villalta, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pathogens and Immunity 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046838/
https://www.ncbi.nlm.nih.gov/pubmed/27709126
http://dx.doi.org/10.20411/pai.v1i2.114