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Epitope Capsid-Incorporation: A New Effective Approach for Vaccine Development for Chagas Disease
BACKGROUND: Previously we reported that a hexon-modified adenovirus (Ad) vector containing the invasive neutralizing epitope of Trypanosoma cruzi (T. cruzi) trypomastigote gp83 (Ad5-gp83) provided immunoprotection against T. cruzi infection. The purpose of this work was to design an improved vaccine...
Autores principales: | Matthews, Qiana L., Farrow, Anitra L., Rachakonda, Girish, Gu, Linlin, Nde, Pius, Krendelchtchikov, Alexandre, Pratap, Siddharth, Sakhare, Shruti S., Sabbaj, Steffanie, Lima, Maria F., Villalta, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pathogens and Immunity
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046838/ https://www.ncbi.nlm.nih.gov/pubmed/27709126 http://dx.doi.org/10.20411/pai.v1i2.114 |
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