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Molecular stripping, targets and decoys as modulators of oscillations in the NF-κB/IκBα/DNA genetic network

Eukaryotic transcription factors in the NF-κB family are central components of an extensive genetic network that activates cellular responses to inflammation and to a host of other external stressors. This network consists of feedback loops that involve the inhibitor IκBα, numerous downstream functi...

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Detalles Bibliográficos
Autores principales: Wang, Zhipeng, Potoyan, Davit A., Wolynes, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046959/
https://www.ncbi.nlm.nih.gov/pubmed/27683001
http://dx.doi.org/10.1098/rsif.2016.0606