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In vivo dual-delivery of glucagon like peptide-1 (GLP-1) and dipeptidyl peptidase-4 (DPP4) inhibitor through composites prepared by microfluidics for diabetes therapy

Oral delivery of proteins is still a challenge in the pharmaceutical field. Nanoparticles are among the most promising carrier systems for the oral delivery of proteins by increasing their oral bioavailability. However, most of the existent data regarding nanosystems for oral protein delivery is fro...

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Detalles Bibliográficos
Autores principales: Araújo, F., Shrestha, N., Gomes, M. J., Herranz-Blanco, B., Liu, D., Hirvonen, J. J., Granja, P. L., Santos, H. A., Sarmento, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047059/
https://www.ncbi.nlm.nih.gov/pubmed/27150301
http://dx.doi.org/10.1039/c6nr00294c