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Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis

Fungal pathogens have evolved diverse strategies to sense host-relevant cues and coordinate cellular responses, which enable virulence and drug resistance. Defining circuitry controlling these traits opens new opportunities for chemical diversity in therapeutics, as the cognate inhibitors are rarely...

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Detalles Bibliográficos
Autores principales: Polvi, Elizabeth J., Averette, Anna F., Lee, Soo Chan, Kim, Taeyup, Bahn, Yong-Sun, Veri, Amanda O., Robbins, Nicole, Heitman, Joseph, Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047589/
https://www.ncbi.nlm.nih.gov/pubmed/27695031
http://dx.doi.org/10.1371/journal.pgen.1006350