CERAMIC: Case-Control Association Testing in Samples with Related Individuals, Based on Retrospective Mixed Model Analysis with Adjustment for Covariates

We consider the problem of genetic association testing of a binary trait in a sample that contains related individuals, where we adjust for relevant covariates and allow for missing data. We propose CERAMIC, an estimating equation approach that can be viewed as a hybrid of logistic regression and li...

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Detalles Bibliográficos
Autores principales: Zhong, Sheng, Jiang, Duo, McPeek, Mary Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047592/
https://www.ncbi.nlm.nih.gov/pubmed/27695091
http://dx.doi.org/10.1371/journal.pgen.1006329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047592/
https://www.ncbi.nlm.nih.gov/pubmed/27695091
http://dx.doi.org/10.1371/journal.pgen.1006329

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