Structural Basis of Mucopolysaccharidosis Type II and Construction of a Database of Mutant Iduronate 2-Sulfatases

Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is an X-linked genetic disorder caused by a deficiency of iduronate 2-sulfatase (IDS), and missense mutations comprising about 30% of the mutations responsible for MPS II result in heterogeneous phenotypes ranging from the severe to the attenua...

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Detalles Bibliográficos
Autores principales: Saito, Seiji, Ohno, Kazuki, Okuyama, Torayuki, Sakuraba, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047593/
https://www.ncbi.nlm.nih.gov/pubmed/27695081
http://dx.doi.org/10.1371/journal.pone.0163964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047593/
https://www.ncbi.nlm.nih.gov/pubmed/27695081
http://dx.doi.org/10.1371/journal.pone.0163964

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