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Optimized Fragmentation Regime for Diazirine Photo-Cross-Linked Peptides

[Image: see text] Cross-linking/mass spectrometry has evolved into a robust technology that reveals structural insights into proteins and protein complexes. We leverage a new tribrid instrument with improved fragmentation capacities in a systematic comparison to identify which fragmentation method w...

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Detalles Bibliográficos
Autores principales: Giese, Sven H., Belsom, Adam, Rappsilber, Juri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047652/
https://www.ncbi.nlm.nih.gov/pubmed/27454319
http://dx.doi.org/10.1021/acs.analchem.6b02082