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A mouse model for ulcerative colitis based on NOD-scid IL2R γ(null) mice reconstituted with peripheral blood mononuclear cells from affected individuals
Animal models reflective of ulcerative colitis (UC) remain a major challenge, and yet are crucial to understand mechanisms underlying the onset of disease and inflammatory characteristics of relapses and remission. Mouse models in which colitis-like symptoms are induced through challenge with toxins...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047691/ https://www.ncbi.nlm.nih.gov/pubmed/27491073 http://dx.doi.org/10.1242/dmm.025452 |