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Small heat shock proteins mediate cell-autonomous and -nonautonomous protection in a Drosophila model for environmental-stress-induced degeneration

Cell and tissue degeneration, and the development of degenerative diseases, are influenced by genetic and environmental factors that affect protein misfolding and proteotoxicity. To better understand the role of the environment in degeneration, we developed a genetic model for heat shock (HS)-stress...

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Detalles Bibliográficos
Autores principales: Kawasaki, Fumiko, Koonce, Noelle L., Guo, Linda, Fatima, Shahroz, Qiu, Catherine, Moon, Mackenzie T., Zheng, Yunzhen, Ordway, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047692/
https://www.ncbi.nlm.nih.gov/pubmed/27483356
http://dx.doi.org/10.1242/dmm.026385