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Sar1 localizes at the rims of COPII-coated membranes in vivo

The Sar1 GTPase controls coat assembly on coat protein complex II (COPII)-coated vesicles, which mediate protein transport from the endoplasmic reticulum (ER) to the Golgi. The GTP-bound form of Sar1, activated by the ER-localized guanine nucleotide exchange factor (GEF) Sec12, associates with the E...

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Detalles Bibliográficos
Autores principales: Kurokawa, Kazuo, Suda, Yasuyuki, Nakano, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047700/
https://www.ncbi.nlm.nih.gov/pubmed/27432890
http://dx.doi.org/10.1242/jcs.189423