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MicroRNA profiling of patient plasma for clinical trials using bioinformatics and biostatistical approaches

BACKGROUND: MicroRNAs (miRNAs) are short noncoding RNAs that function to repress translation of mRNA transcripts and contribute to the development of cancer. We hypothesized that miRNA array-based technologies work best for miRNA profiling of patient-derived plasma samples when the techniques and pa...

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Detalles Bibliográficos
Autores principales: Markowitz, Joseph, Abrams, Zachary, Jacob, Naduparambil K, Zhang, Xiaoli, Hassani, John N, Latchana, Nicholas, Wei, Lai, Regan, Kelly E, Brooks, Taylor R, Uppati, Sarvani R, Levine, Kala M, Bekaii-Saab, Tanios, Kendra, Kari L, Lesinski, Gregory B, Howard, J Harrison, Olencki, Thomas, Payne, Philip R, Carson, William E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047719/
https://www.ncbi.nlm.nih.gov/pubmed/27729802
http://dx.doi.org/10.2147/OTT.S106288