BET inhibitors in the treatment of hematologic malignancies: current insights and future prospects

The bromodomain and extra-terminal (BET) family of proteins are important epigenetic regulators involved in promoting gene expression of critical oncogenes. BET inhibitors have been demonstrated to repress c-Myc expression, and were initially shown to have efficacy in a number of c-Myc-dependent hem...

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Detalles Bibliográficos
Autores principales: Abedin, Sameem M, Boddy, Craig S, Munshi, Hidayatullah G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047722/
https://www.ncbi.nlm.nih.gov/pubmed/27729803
http://dx.doi.org/10.2147/OTT.S100515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047722/
https://www.ncbi.nlm.nih.gov/pubmed/27729803
http://dx.doi.org/10.2147/OTT.S100515

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