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BET inhibitors in the treatment of hematologic malignancies: current insights and future prospects
The bromodomain and extra-terminal (BET) family of proteins are important epigenetic regulators involved in promoting gene expression of critical oncogenes. BET inhibitors have been demonstrated to repress c-Myc expression, and were initially shown to have efficacy in a number of c-Myc-dependent hem...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047722/ https://www.ncbi.nlm.nih.gov/pubmed/27729803 http://dx.doi.org/10.2147/OTT.S100515 |