CX-5461 induces autophagy and inhibits tumor growth via mammalian target of rapamycin-related signaling pathways in osteosarcoma

Osteosarcoma (OS) is the most common primary bone tumor, but molecular mechanisms of the disease have not been well understood, and treatment of metastatic OS remains a challenge. Rapid ribosomal RNA synthesis in cancer is transcribed by RNA polymerase I, which results in unbridled cell growth. The...

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Detalles Bibliográficos
Autores principales: Li, Leiming, Li, Yan, Zhao, Jiansong, Fan, Shuli, Wang, Liguo, Li, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047727/
https://www.ncbi.nlm.nih.gov/pubmed/27729807
http://dx.doi.org/10.2147/OTT.S104513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047727/
https://www.ncbi.nlm.nih.gov/pubmed/27729807
http://dx.doi.org/10.2147/OTT.S104513

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