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Characterization of TLR-induced inflammatory responses in COPD and control lung tissue explants

PURPOSE: Viruses are a common cause of exacerbations in chronic obstructive pulmonary disease (COPD). They activate toll-like receptors (TLRs) 3, 7, and 8, leading to a pro-inflammatory response. We have characterized the responses of TLR3 and TLR7/8 in lung tissue explants from COPD patients and co...

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Detalles Bibliográficos
Autores principales: Pomerenke, Anna, Lea, Simon R, Herrick, Sarah, Lindsay, Mark A, Singh, Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047739/
https://www.ncbi.nlm.nih.gov/pubmed/27729782
http://dx.doi.org/10.2147/COPD.S105156