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Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

Exosomes are small vesicles that are secreted from metazoan cells and may convey selected membrane proteins and small RNAs to target cells for the control of cell migration, development and metastasis. To study the mechanisms of RNA packaging into exosomes, we devised a purification scheme based on...

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Detalles Bibliográficos
Autores principales: Shurtleff, Matthew J, Temoche-Diaz, Morayma M, Karfilis, Kate V, Ri, Sayaka, Schekman, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047747/
https://www.ncbi.nlm.nih.gov/pubmed/27559612
http://dx.doi.org/10.7554/eLife.19276