Cargando…

A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?

Cells regularly synthesize new proteins to replace old and abnormal proteins for normal cellular functions. Two significant protein quality control pathways inside the cellular milieu are ubiquitin proteasome system (UPS) and autophagy. Autophagy is known for bulk clearance of cytoplasmic aggregated...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Vibhuti, Amanullah, Ayeman, Upadhyay, Arun, Mishra, Ribhav, Kumar, Amit, Mishra, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047891/
https://www.ncbi.nlm.nih.gov/pubmed/27757073
http://dx.doi.org/10.3389/fnmol.2016.00093