Kinetic analysis of the translocator protein positron emission tomography ligand [(18)F]GE-180 in the human brain

PURPOSE: PET can image neuroinflammation by targeting the translocator protein (TSPO), which is upregulated in activated microglia. The high nonspecific binding of the first-generation TSPO radioligand [(11)C]PK-11195 limits accurate quantification. [(18)F]GE-180, a novel TSPO ligand, displays super...

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Detalles Bibliográficos
Autores principales: Feeney, Claire, Scott, Gregory, Raffel, Joel, Roberts, S., Coello, Christopher, Jolly, Amy, Searle, Graham, Goldstone, A. P., Brooks, David J., Nicholas, Richard S., Trigg, William, Gunn, Roger N., Sharp, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047949/
https://www.ncbi.nlm.nih.gov/pubmed/27349244
http://dx.doi.org/10.1007/s00259-016-3444-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047949/
https://www.ncbi.nlm.nih.gov/pubmed/27349244
http://dx.doi.org/10.1007/s00259-016-3444-z

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