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Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer
Mechanistic/mammalian target of rapamycin (mTOR) has emerged as a new potential therapeutic target for gastric cancer. Rapamycin and rapamycin analogs are undergoing clinical trials and have produced clinical responses in a subgroup of cancer patients. However, monotherapy with rapamycin at safe dos...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048112/ https://www.ncbi.nlm.nih.gov/pubmed/27697670 http://dx.doi.org/10.1016/j.redox.2016.09.006 |