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Acid-sensing ion channel 1a regulates the survival of nucleus pulposus cells in the acidic environment of degenerated intervertebral discs

OBJECTIVE(S): Activation of acid-sensing ion channel 1a (ASIC1a) is responsible for tissue injury caused by acidosis in nervous systems. But its physiological and pathological roles in nucleus pulposus cells (NPCs) are unclear. The aim of this study is to investigate whether ASIC1a regulates the sur...

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Detalles Bibliográficos
Autores principales: Cai, Feng, Wang, Feng, Hong, Xin, Xie, Xin-Hui, Shi, Rui, Xie, Zhi-Yang, Wu, Xiao-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048115/
https://www.ncbi.nlm.nih.gov/pubmed/27746861