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Thymoquinone synergistically potentiates temozolomide cytotoxicity through the inhibition of autophagy in U87MG cell line

OBJECTIVE(S): Glioblastoma multiforme (GBM) is one of the most lethal forms of human cancer and temozolomide (TMZ) is currently part of the standard treatment for this disease. Combination therapy using natural substances can enhance the anti-cancer activity of TMZ. The purpose of this study was to...

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Detalles Bibliográficos
Autores principales: Pazhouhi, Mona, Sariri, Reyhaneh, Rabzia, Arezou, Khazaei, Mozafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048126/
https://www.ncbi.nlm.nih.gov/pubmed/27746872