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Aldo-keto reductase 1C1 induced by interleukin-1β mediates the invasive potential and drug resistance of metastatic bladder cancer cells

In treating bladder cancer, determining the molecular mechanisms of tumor invasion, metastasis, and drug resistance are urgent to improving long-term patient survival. One of the metabolic enzymes, aldo-keto reductase 1C1 (AKR1C1), plays an essential role in cancer invasion/metastasis and chemoresis...

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Detalles Bibliográficos
Autores principales: Matsumoto, Ryuji, Tsuda, Masumi, Yoshida, Kazuhiko, Tanino, Mishie, Kimura, Taichi, Nishihara, Hiroshi, Abe, Takashige, Shinohara, Nobuo, Nonomura, Katsuya, Tanaka, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048132/
https://www.ncbi.nlm.nih.gov/pubmed/27698389
http://dx.doi.org/10.1038/srep34625