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The pioneering role of PRDM9 indel mutations in tarsier evolution

PRDM9 is currently the sole speciation gene found in vertebrates causing hybrid sterility probably due to incompatible alleles. Its role in defining the double strand break loci during the meiotic prophase I is crucial for proper chromosome segregation. Therefore, the rapid turnover of the loci dete...

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Detalles Bibliográficos
Autores principales: Heerschop, Sacha, Zischler, Hans, Merker, Stefan, Perwitasari-Farajallah, Dyah, Driller, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048142/
https://www.ncbi.nlm.nih.gov/pubmed/27698394
http://dx.doi.org/10.1038/srep34618